City profile
Sikeston, MO
Scott County · Population 16,320
Sikeston is a town in Scott County, MO with about 16,320 residents and a typical home value near $169,000. It is 125 miles from St. Louis, MO, which shapes its climate, healthcare access and amenities.
Climate
Climate type
Four seasons
Winter avg
36°F
Summer avg
82°F
Sunny days / yr
205
Home prices & cost of living
Median home price
$168,800
Typical monthly housing
$1,053
Cost of living (100 = U.S.)
82
Taxes
- Property tax
- 0.97%
- State income tax (top)
- 4.7%
- Social Security
- Not taxed
- Pensions
- Partly exempt
- Sales tax (state + avg. local)
- 8.39%
FEMA natural hazard risk
Relatively Low · county score 80/100
Top hazards: Earthquake, Ice storm, Tornado
Nearest major airport
129 mi to Frederick W. Smith International Airport (MEM)
Political lean (2024 county vote)
Leans Republican · 20% Democratic / 79% Republican
Community
Population
16,320
Black population
21.4%
County
Scott County
Detailed crime figures are available for our 201 hand-researched cities.
2025–2026 trends
2026 market trends
- ▸Home prices are still rising in 2026 — good for long-term value, less room to negotiate
- ▸Climate/cost risks to check: tornadoes
Highlights
- About 16,320 residents
- Typical home value about $169,000
- 125 miles from St. Louis, MO
Trade-offs
- Smaller community with fewer local amenities
- Scores for this place are estimated from Census data and the nearest major city
Figures are estimates from public sources (see How we match). Verify before making decisions.