City profile
Cape Girardeau, MO
Cape Girardeau County · Population 40,344
Cape Girardeau is a town in Cape Girardeau County, MO with about 40,344 residents and a typical home value near $196,000. It is 97 miles from St. Louis, MO, which shapes its climate, healthcare access and amenities.
Climate
Climate type
Four seasons
Winter avg
35°F
Summer avg
81°F
Sunny days / yr
205
Home prices & cost of living
Median home price
$196,300
Typical monthly housing
$1,225
Cost of living (100 = U.S.)
86
Taxes
- Property tax
- 0.97%
- State income tax (top)
- 4.7%
- Social Security
- Not taxed
- Pensions
- Partly exempt
- Sales tax (state + avg. local)
- 8.39%
FEMA natural hazard risk
Relatively Moderate · county score 86/100
Top hazards: Earthquake, Ice storm, Heat wave
Nearest major airport
109 mi to St. Louis Lambert International Airport (STL)
Political lean (2024 county vote)
Leans Republican · 26% Democratic / 73% Republican
Community
Population
40,344
Black population
13.2%
County
Cape Girardeau County
Detailed crime figures are available for our 201 hand-researched cities.
2025–2026 trends
2026 market trends
- ▸Home prices are still rising in 2026 — good for long-term value, less room to negotiate
- ▸Climate/cost risks to check: tornadoes
Highlights
- About 40,344 residents
- Typical home value about $196,000
- 97 miles from St. Louis, MO
Trade-offs
- Scores for this place are estimated from Census data and the nearest major city
Figures are estimates from public sources (see How we match). Verify before making decisions.